Dr Victoria Allen-Baume
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Email
v.allen-baume@essex.ac.uk -
Telephone
+44 (0) 1206 872231
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Location
4.111, Colchester Campus
Teaching and supervision
Current teaching responsibilities
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Biochemistry of Macromolecules (BS131)
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Chemistry for Biology (IA123)
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General and Organic Chemistry (BS132)
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Transferable Skills in Life Sciences (BS143)
Publications
Journal articles (15)
Cooper, CE., Simons, M., Dyson, A., Leiva Eriksson, N., Silkstone, GGA., Syrett, N., Allen-Baume, V., Bülow, L., Ronda, L., Mozzarelli, A., Singer, M. and Reeder, BJ., (2024). Taming hemoglobin chemistry—a new hemoglobin-based oxygen carrier engineered with both decreased rates of nitric oxide scavenging and lipid oxidation. Experimental & Molecular Medicine. 56 (10), 2260-2270
Cooper, CE., Silkstone, GGA., Simons, M., Gretton, S., Rajagopal, BS., Allen-Baume, V., Syrett, N., Shaik, T., Popa, G., Sheng, X., Bird, M., Choi, J-W., Piano, R., Ronda, L., Bettati, S., Paredi, G., Mozzarelli, A. and Reeder, BJ., (2020). Engineering hemoglobin to enable homogenous PEGylation without modifying protein functionality. Biomaterials Science. 8 (14), 3896-3906
Simons, M., Gretton, S., Silkstone, GG., Rajagopal, BS., Allen-Baume, V., Syrett, N., Shaik, T., Eriksson, N., Ronda, L., Mozzarelli, A., Strader, MB., Alayash, AI., Reeder, BJ. and Cooper, CE., (2018). Comparison of the oxidative reactivity of recombinant fetal and adult human hemoglobin: implications for the design of hemoglobin-based oxygen carriers.. Bioscience Reports. 38 (4), BSR20180370-
Cheruvara, H., Allen-Baume, VL., Kad, NM. and Mason, JM., (2015). Intracellular Screening of a Peptide Library to Derive a Potent Peptide Inhibitor of α-Synuclein Aggregation. Journal of Biological Chemistry. 290 (12), 7426-7435
Cosker, KE., Shadan, S., van Diepen, M., Morgan, C., Li, M., Allen-Baume, V., Hobbs, C., Doherty, P., Cockcroft, S. and Eickholt, BJ., (2008). Regulation of PI3K signalling by the phosphatidylinositol transfer protein PITPα during axonal extension in hippocampal neurons. Journal of Cell Science. 121 (6), 796-803
Morgan, CP., Allen-Baume, V., Radulovic, M., Li, M., Skippen, A. and Cockcroft, S., (2006). Differential expression of a C-terminal splice variant of phosphatidylinositol transfer protein β lacking the constitutive-phosphorylated Ser262 that localizes to the Golgi compartment. Biochemical Journal. 398 (3), 411-421
Morgan, CP., Skippen, A., Segui, B., Ball, A., Allen-Baume, V., Larijani, B., Murray-Rust, J., McDonald, N., Sapkota, G., Morrice, N. and Cockcroft, S., (2004). Phosphorylation of a Distinct Structural Form of Phosphatidylinositol Transfer Protein α at Ser166 by Protein Kinase C Disrupts Receptor-mediated Phospholipase C Signaling by Inhibiting Delivery of Phosphatidylinositol to Membranes. Journal of Biological Chemistry. 279 (45), 47159-47171
Larijani, B., Allen-Baume, V., Morgan, CP., Li, M. and Cockcroft, S., (2003). EGF Regulation of PITP Dynamics Is Blocked by Inhibitors of Phospholipase C and of the Ras-MAP Kinase Pathway. Current Biology. 13 (1), 78-84
Allen-Baume, V., Ségui, B. and Cockcroft, S., (2002). Current thoughts on the phosphatidylinositol transfer protein family. FEBS Letters. 531 (1), 74-80
O'Luanaigh, N., Pardo, R., Fensome, A., Allen-Baume, V., Jones, D., Holt, MR. and Cockcroft, S., (2002). Continual Production of Phosphatidic Acid by Phospholipase D Is Essential for Antigen-stimulated Membrane Ruffling in Cultured Mast Cells. Molecular Biology of the Cell. 13 (10), 3730-3746
SÉGUI, B., ALLEN-BAUME, V. and COCKCROFT, S., (2002). Phosphatidylinositol transfer protein β displays minimal sphingomyelin transfer activity and is not required for biosynthesis and trafficking of sphingomyelin. Biochemical Journal. 366 (1), 23-34
TAKEUCHI, H., OIKE, M., PATERSON, HF., ALLEN, V., KANEMATSU, T., ITO, Y., ERNEUX, C., KATAN, M. and HIRATA, M., (2000). Inhibition of Ca2+ signalling by p130, a phospholipase-C-related catalytically inactive protein: critical role of the p130 pleckstrin homology domain. Biochemical Journal. 349 (1), 357-368
Yamamoto, T., Takeuchi, H., Kanematsu, T., Allen, V., Yagisawa, H., Kikkawa, U., Watanabe, Y., Nakasima, A., Katan, M. and Hirata, M., (1999). Involvement of EF hand motifs in the Ca2+‐dependent binding of the pleckstrin homology domain to phosphoinositides. European Journal of Biochemistry. 265 (1), 481-490
Yagisawa, H., Sakuma, K., Paterson, HF., Cheung, R., Allen, V., Hirata, H., Watanabe, Y., Hirata, M., Williams, RL. and Katan, M., (1998). Replacements of Single Basic Amino Acids in the Pleckstrin Homology Domain of Phospholipase C-δ1 Alter the Ligand Binding, Phospholipase Activity, and Interaction with the Plasma Membrane. Journal of Biological Chemistry. 273 (1), 417-424
ALLEN, V., SWIGART, P., CHEUNG, R., COCKCROFT, S. and KATAN, M., (1997). Regulation of inositol lipid-specific phospholipase Cδ by changes in Ca2+ ion concentrations. Biochemical Journal. 327 (2), 545-552
