Chiemeziem Njoku
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Email
cn23535@essex.ac.uk -
Location
Colchester Campus
Profile
- endocrine disrupters, prostate cancer, androgen receptor signalling cell culture, cloning, luciferase assay, western blotting, etc
Qualifications
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Master of Science in Biochemistry ( Nutrition and Toxicology) University of Port Harcourt, Nigeria (2014)
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Professional Diploma in Education Federal College of Education (Technical), Omoku (2016)
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Bachelor of Science in Biochemistry Niger Delta University (2008)
Research and professional activities
Thesis
Investigation of the Effect of Environmental Endocrine Disrupters upon Steroid Receptor Signalling
Androgen Receptor (AR), part of the steroid hormone receptor family, mediates androgen functions by binding to DNA sequences that regulate androgen-responsive genes. Androgens are known to promote prostate cancer. This study aims to evaluate the impact of environmental endocrine chemicals (EDCs), which are thought to inhibit AR activity.
Supervisor: Professor Corinne Whitby , Dr Greg Brooke
Research interests
Prostate cancer
The androgen receptor (AR), functioning as a transcription factor, plays a crucial role in driving prostate cancer progression by regulating gene expression linked to cell growth. We are interested on the impact of environmental endocrine disruptors (EDs), which are commonly found in everyday food and plastics. These EDs possess some structural similarities to androgens, enabling them to mimic or block natural hormones, which can lead to altered gene regulation.
