People

Dr Angela Pine

Lecturer
School of Life Sciences
Dr Angela Pine

Profile

Biography

Research Interests: My research focuses on the early detection, prevention and management of Human Papillomavirus (HPV) infections and associated diseases. My group investigates factors associated with persistent infection and develops novel treatment modalities. We work closely with other universities, industry and key stakeholders to develop diagnostic solutions and improve access to cervical screening whilst reducing health inequalities globally. Investigating the impact of health-literacy on HPV vaccination uptake and cervical screening guidance adherence. Specialising in functional nucleic acids (DNAzymes, RNA-cleaving DNAzymes), nucleic acid based nanoparticles, molecular biology, and cancer research. Skilled in predictive modelling of nucleic acid interactions, computational modelling and machine learning using R as well as having 'wet-lab' expertise. I have a passion for biologically inspired engineering, designing and developing new ways to use biological design in innovations that answer unmet scientific need. Trained as an HCPC registered Biomedical Scientist. Fellow of the Institute of Biomedical Science. Member of the IBMS Cellular Pathology Specialist Advisory Panel. Masters by dissertation in Cell & Molecular Biology. Scholarship PhD in Cell & Molecular Biology, developing a novel gene therapy and nanoparticle delivery system for castrate resistant prostate cancer (end-stage) resulting in 2 patents (Pine et al., 2023). Founder of 10zyme, a company that aims to make cervical screening accessible to all. Member of the HPV Coalition delivering a roadmap to the UK governments on the elimination of HPV-related cancers.

Qualifications

  • PhD Cell & Molecular Biology University of Essex, (2021)

  • MSc by dissertation Cell & Molecular Biology University of Essex, (2016)

  • BSc Biomedical Science University of Essex, (2014)

Appointments

University of Essex

  • Lecturer, School of Life Sciences, University of Essex (1/10/2022 - present)

Research and professional activities

Research interests

HPV and HPV-related cancers

Key words: HPV
Open to supervise

Diagnostic development

Key words: Diagnostics

Therapeutic design & development

Key words: Therapeutics
Open to supervise

Nanoparticle delivery of nucleic acid based treatments

Key words: Nanoparticles
Open to supervise

Human microbiomes and disease (focus on microbiomes of the female reproductive tract)

Key words: Microbiome
Open to supervise

Mental health impact of HPV/HPV-related cancer diagnosis

Key words: mental health

Patient experiences of the NHS cervical screening programme in England, Scotland, and Wales

Key words: cervical screening

Awareness and knowledge of HPV and cervical cancer

Key words: HPV

Teaching and supervision

Current teaching responsibilities

  • Anatomy and Physiology (BS161)

  • Biomedical Science: Practice and Employability (BS214)

  • Cell Biology (BS225)

  • Cell Biology and Cellular Pathology (BS238)

  • Principles of Molecular Virology (BS310)

  • Research Project in Biomedical Science (BS831)

Publications

Journal articles (2)

Pine, AC., Brooke, GN. and Marco, A., (2023). A computational approach to identify efficient RNA cleaving 10-23 DNAzymes.. NAR Genomics and Bioinformatics. 5 (1), lqac098-

Pine, AC., Fioretti, FF., Brooke, GN. and Bevan, CL., (2016). Advances in genetics: widening our understanding of prostate cancer. F1000Research. 5, 1512-1512

Contact

acpine@essex.ac.uk

Location:

Colchester Campus

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